If this occurs, treatment should be instituted with other appropriate agents as indicated.
Use of topical antibiotic and antifungals may permit overgrowth of non-susceptible bacterial, fungi or yeast. Antibiotic susceptibility of the pathogenic organism(s) should be determined prior to use of this preparation. Do not use in dogs with known perforation of eardrums.ĬAUTIONS: Prior to treatment, it is recommended to conduct a clinical evaluation for evidence of hearing deficit and/or vestibular disorder. Concomitant use of drugs known to induce ototoxicity should be avoided. If hypersensitivity to any of the components occurs, treatment should be discontinued and appropriate alternate therapy instituted. Do not exceed the recommended period of treatment or frequency of application. Massage the external ear carefully after medication is instilled to assure proper distribution. Dogs weighing 15 kg or more: 8 drops for the 7.5 g, 12.5 g, 15 g and 30 g package sizes or 4 drops, for the 215 g package size, per affected ear. Dogs weighing less than 15 kg: 4 drops for the 7.5 g, 12.5 g, 15 g and 30 g package sizes or 2 drops, for the 215 g package size, per affected ear. Instill OTOMAX ointment into the cleaned external ear canal twice daily for 7 days. Shake well before use when using the 12.5 g, 30 g and 215 g bottles. Excessive hair should be removed from the treatment area of the external ear.
Remove foreign material, debris, crusted exudates, etc., with suitable non-irritating solutions. The external ear and ear canal should be properly cleaned and dried before treatment. OTOMAX is indicated for the treatment of canine acute and chronic otitis externa associated with yeast ( Malassezia pachydermatis, formerly Pityrosporum canis) and/or bacteria susceptible to gentamicin. Gentamicin as sulfate is a water soluble (bactericidal) antibiotic of the aminoglycoside group, derived from Micromonospora, an actinomycete.īetamethasone valerate is a synthetic glucocorticoid derivative of prednisolone.Ĭlotrimazole is a synthetic antifungal belonging to the imidazole family.Įach gram of OTOMAX ointment contains 3 mg gentamicin as gentamicin sulfate USP, 1 mg betamethasone as betamethasone valerate USP, and 10 mg clotrimazole USP in a mineral oil based vehicle containing a plasticized hydrocarbon gel. Antibiotic, Anti-inflammatory, Antifungal
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